NYT articles claims LDL cannot be too low

I am posting this article just so I have an article that maintains the standard “party” line of the anticholesterol crowd.
February 9, 2010
Q & A

Low LDL Levels

Q. Can my LDL, my “bad” cholesterol, get too low?

A. It is possible but unlikely. Some medical authorities have suggested that levels of low-density lipoprotein in the bloodstream can be pushed too low, and they emphasize that the goal of medication for cholesterol reduction to reduce cardiac risk should be to get thelipids in proper balance.

But recent research concluded that few if any problems resulted from the reduction of LDL levels below the usual guidelines. A 2005 study in The Journal of the American College of Cardiology compared patients treated with statins that pushed their LDL levels below the accepted goal of 80 to 100 milligrams per deciliter of blood with those at recommended levels and found “no adverse effect on safety” and “apparent improved clinical efficacy.”

Updated guidelines endorsed by the National Heart, Lung and Blood Institute say that LDL-lowering treatment to get levels below 70 milligrams is an option for patients who are at very high risk of cardiac disease.

In a debate published online by Current Controlled Trials in Cardiovascular Medicine, even those who argued against drastic reduction goals said the most valuable therapeutic results were achieved with an LDL reduction of 30 percent to 40 percent in high-risk patients, regardless of the original level. They also pointed out that while adverse effects of low LDL have been reported at concentrations below 25 milligrams per deciliter, that value is rarely achieved with statin therapy in high-risk patients.


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