Avandia promoters and conflicts of interest

Difficult to know if the favorable opinions or the ties to the pharma company came first, but it is not unreasonable to have our suspicions.

from a Reuter’s article: http://tiny.cc/TLFfG

A team at the Mayo Clinic in Rochester, Minnesota, pored through more than 200 scientific studies and commentaries that offered positive opinions about the drug after a May 2007 study suggested Avandia significantly increased the risk of heart attacks.

They found that 94 percent of the authors who defended the drug, known generically as rosiglitazone, had ties to drug companies, and nearly half had financial ties that presented a conflict of interest.

“It was almost three to four times more likely that somebody who had a relationship with a pharmaceutical company had a favorable opinion about the medication,” Dr Victor Montori of the Mayo Clinic, whose study appears in the British Medical Journal, said in a telephone interview.

Montori looked at the financial relationships of researchers who had ties with pharmaceutical companies in general, and particularly those who wrote about rosiglitazone or the rival drug pioglitazone, made by Takeda Pharmaceutical Co Ltd under the brand name Actos.

“If you were to look at the proportion of people with favorable opinions, 94 percent of them had a relationship with a pharmaceutical company,” Montori said.

for much more

http://tiny.cc/TLFfG

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